{"id":2536,"date":"2024-04-28T18:31:30","date_gmt":"2024-04-28T16:31:30","guid":{"rendered":"https:\/\/neurocirugialmeria.com\/?p=2536"},"modified":"2024-04-28T18:31:30","modified_gmt":"2024-04-28T16:31:30","slug":"reparacion-de-circuitos-cerebrales-con-celulas-procedentes-de-diferentes-especies-resultados-de-una-investigacion","status":"publish","type":"post","link":"https:\/\/neurocirugialmeria.com\/en\/2024\/04\/28\/reparacion-de-circuitos-cerebrales-con-celulas-procedentes-de-diferentes-especies-resultados-de-una-investigacion\/","title":{"rendered":"Reparaci\u00f3n de circuitos cerebrales con c\u00e9lulas procedentes de diferentes especies: Resultados de una investigaci\u00f3n"},"content":{"rendered":"

La revista Cell<\/a> acaba de publicar los resultados de un trabajo en el que investigadores afincados en Estados Unidos con participaci\u00f3n espa\u00f1ola han logrado generar animales en cuyo cerebro se hayan integradas c\u00e9lulas procedentes de otra especie.<\/p>\n\n\n\n

De esta manera la participaci\u00f3n de c\u00e9lulas madre de rata durante el per\u00edodo embrionario del rat\u00f3n permiti\u00f3 reparar circuitos cerebrales da\u00f1ados o silenciados en \u00e9stos, de forma que se observ\u00f3 c\u00f3mo las c\u00e9lulas de la rata presentaban la capacidad para integrarse en dichos circuitos y suplir la funci\u00f3n que hab\u00eda sido da\u00f1ada.<\/p>\n\n\n\n

As\u00ed, los autores apreciaron c\u00f3mo ratones que debido a silenciamiento gen\u00e9tico presentaban da\u00f1ados los circuitos cerebrales de la olfaci\u00f3n pudieron recuperar esta funci\u00f3n gracias a la participaci\u00f3n en el per\u00edodo embrionario de c\u00e9lulas madre de la rata.<\/p>\n\n\n\n

Fuente: <\/strong>Throesch BT, Bin Imtiaz MK, Mu\u00f1oz-Casta\u00f1eda R, Sakurai M, Hartzell AL, James KN, Rodriguez AR, Martin G, Lippi G, Kupriyanov S, Wu Z, Osten P, Izpisua Belmonte JC, Wu J, Baldwin KK. Functional sensory circuits built from neurons of two species. Cell. 2024 Apr 25;187(9):2143-2157.e15.\u00a0<\/a><\/p>","protected":false},"excerpt":{"rendered":"

La revista Cell acaba de publicar los resultados de un trabajo en el que investigadores afincados en Estados Unidos con participaci\u00f3n espa\u00f1ola han logrado generar animales en cuyo cerebro se hayan integradas c\u00e9lulas procedentes de otra especie. De esta manera la participaci\u00f3n de c\u00e9lulas madre de rata durante el per\u00edodo embrionario del rat\u00f3n permiti\u00f3 reparar…<\/p>","protected":false},"author":183523340,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false,"jetpack_post_was_ever_published":false},"categories":[1771],"tags":[],"class_list":["post-2536","post","type-post","status-publish","format-standard","hentry","category-sin-categoria"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_likes_enabled":true,"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pbS7CP-EU","jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts\/2536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/users\/183523340"}],"replies":[{"embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/comments?post=2536"}],"version-history":[{"count":2,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts\/2536\/revisions"}],"predecessor-version":[{"id":2538,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts\/2536\/revisions\/2538"}],"wp:attachment":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/media?parent=2536"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/categories?post=2536"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/tags?post=2536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}