{"id":2448,"date":"2024-03-18T18:49:08","date_gmt":"2024-03-18T17:49:08","guid":{"rendered":"https:\/\/neurocirugialmeria.com\/?p=2448"},"modified":"2024-03-18T18:50:33","modified_gmt":"2024-03-18T17:50:33","slug":"17-de-marzo-de-2024","status":"publish","type":"post","link":"https:\/\/neurocirugialmeria.com\/en\/2024\/03\/18\/17-de-marzo-de-2024\/","title":{"rendered":"Inmunoterapia CAR T en glioblastoma recurrente"},"content":{"rendered":"<p class=\"has-text-align-center wp-block-paragraph\">La revista <a href=\"https:\/\/www.nejm.org\/\">New England Journal of Medicine<\/a> ha publicado recientemente los resultados del tratamiento de glioblastomas recurrentes mediante la administraci\u00f3n intraventricular de inmunoterapia con c\u00e9lulas CAR T antitumorales.<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">Se trata de un estudio piloto donde se emple\u00f3 esta terapia en tres pacientes con glioblastomas recurrentes. Los autores observaron una marcada respuesta en la reducci\u00f3n de la carga tumoral en dos de ellos. Esta respuesta sin embargo no fue mantenida teniendo lugar posteriormente la progresi\u00f3n tumoral.<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">Este estudio abre la posibilidad de una nueva herramienta terap\u00e9utica para el tratamiento del glioma de alto grado, si bien ser\u00e1n necesarios ensayos cl\u00ednicos con mayor n\u00famero de pacientes para establecer su papel.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><span style=\"text-decoration: underline\">Fuente:<\/span><\/strong> <a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2314390?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\">Choi BD, Gerstner ER, Frigault MJ, Leick MB, Mount CW, Balaj L, Nikiforow S, Carter BS, Curry WT, Gallagher K, Maus MV. Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma. N Engl J Med. 2024 Mar 13.<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>La revista New England Journal of Medicine ha publicado recientemente los resultados del tratamiento de glioblastomas recurrentes mediante la administraci\u00f3n intraventricular de inmunoterapia con c\u00e9lulas CAR T antitumorales. Se trata de un estudio piloto donde se emple\u00f3 esta terapia en tres pacientes con glioblastomas recurrentes. Los autores observaron una marcada respuesta en la reducci\u00f3n de&#8230;<\/p>","protected":false},"author":183523340,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_seo_schema_type":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_wpcom_ai_launchpad_first_post":false,"_jetpack_hide_featured_image":false,"_jetpack_featured_image_duplicate_dismissed":0,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false,"jetpack_post_was_ever_published":false},"categories":[1771],"tags":[],"class_list":["post-2448","post","type-post","status-publish","format-standard","hentry","category-sin-categoria"],"jetpack_publicize_connections":[],"jetpack_likes_enabled":true,"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pbS7CP-Du","jetpack-related-posts":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts\/2448","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/users\/183523340"}],"replies":[{"embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/comments?post=2448"}],"version-history":[{"count":4,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts\/2448\/revisions"}],"predecessor-version":[{"id":2452,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts\/2448\/revisions\/2452"}],"wp:attachment":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/media?parent=2448"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/categories?post=2448"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/tags?post=2448"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}