{"id":1773,"date":"2022-11-04T19:25:40","date_gmt":"2022-11-04T18:25:40","guid":{"rendered":"https:\/\/neurocirugialmeria.com\/?p=1773"},"modified":"2022-11-04T19:25:40","modified_gmt":"2022-11-04T18:25:40","slug":"diagnostico-y-tratamiento-precoz-del-glioblastoma-y-su-impacto-en-la-supervivencia","status":"publish","type":"post","link":"https:\/\/neurocirugialmeria.com\/en\/2022\/11\/04\/diagnostico-y-tratamiento-precoz-del-glioblastoma-y-su-impacto-en-la-supervivencia\/","title":{"rendered":"Diagn\u00f3stico y tratamiento precoz del glioblastoma y su impacto en la supervivencia"},"content":{"rendered":"

La revista Neurosurgery<\/a> ha publicado un trabajo en el que autores japoneses analizan el impacto del diagn\u00f3stico y tratamiento precoz en el pron\u00f3stico del glioblastoma.<\/p>\n\n\n\n

Para ello han estudiado de forma retrospectiva un total de 153 pacientes que dividieron entre aquellos diagnosticados antes o despu\u00e9s de los 14 d\u00edas tras la aparici\u00f3n de s\u00edntomas, as\u00ed como los tratados respecto a los 21 y 35 d\u00edas tras el inicio del cuadro.<\/p>\n\n\n\n

Dentro de los diagnosticados antes de los 14 d\u00edas se observo c\u00f3mo el tama\u00f1o del tumor era significativamente menor. En cuanto al tratamiento se diferenciaron tres grupos: tratados en los primeros 21 d\u00edas, entre los 21 y 35 d\u00edas y por \u00faltimo aquellos tratados 35 d\u00edas tras el inicio de los s\u00edntomas. Se observ\u00f3 una diferencia significativa entre la supervivencia de los tratados precozmente, antes de los 21 d\u00edas del inicio del cuadro (28,4 meses) respecto a los tratados de forma tard\u00eda, despu\u00e9s de 35 d\u00edas del inicio de s\u00edntomas (18,7 meses).<\/p>\n\n\n\n

El an\u00e1lisis multivariante mostr\u00f3 como otros factores asociados a un peor pron\u00f3stico la biopsia o resecci\u00f3n parcial, la puntuaci\u00f3n de menor de 60 en la escala KPS y la presencia del gen MGMT en su forma no metilada.<\/p>\n\n\n\n

Fuente: <\/span><\/strong>Kawauchi D, Ohno M, Miyakita Y, Takahashi M, Yanagisawa S, Omura T, Yoshida A, Kubo Y, Igaki H, Ichimura K, Narita Y. Early Diagnosis and Surgical Intervention Within 3 Weeks From Symptom Onset Are Associated With Prolonged Survival of Patients With Glioblastoma. Neurosurgery. 2022 Nov 1;91(5):741-748.<\/a><\/p>","protected":false},"excerpt":{"rendered":"

La revista Neurosurgery ha publicado un trabajo en el que autores japoneses analizan el impacto del diagn\u00f3stico y tratamiento precoz en el pron\u00f3stico del glioblastoma. Para ello han estudiado de forma retrospectiva un total de 153 pacientes que dividieron entre aquellos diagnosticados antes o despu\u00e9s de los 14 d\u00edas tras la aparici\u00f3n de s\u00edntomas, as\u00ed…<\/p>","protected":false},"author":183523340,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_seo_schema_type":"","_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_wpcom_ai_launchpad_first_post":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false,"jetpack_post_was_ever_published":false},"categories":[1771],"tags":[],"class_list":["post-1773","post","type-post","status-publish","format-standard","hentry","category-sin-categoria"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_likes_enabled":true,"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pbS7CP-sB","jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts\/1773","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/users\/183523340"}],"replies":[{"embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/comments?post=1773"}],"version-history":[{"count":2,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts\/1773\/revisions"}],"predecessor-version":[{"id":1775,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/posts\/1773\/revisions\/1775"}],"wp:attachment":[{"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/media?parent=1773"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/categories?post=1773"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neurocirugialmeria.com\/en\/wp-json\/wp\/v2\/tags?post=1773"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}